Nexium (esomeprazole) and Prilosec (omeprazole) are the two drugs that have been widely used for treating heartburn, ulcers, and other acid-related stomach issues. They are most commonly known as proton pump inhibitors, or PPIs, and they play a very effective role in reducing the production of stomach acids.
These drugs are prescribed for acid reflux, gastroesophageal reflux disease (GERD), and peptic ulcers. While they are effective in reducing stomach acid, growing research has raised concerns about their long-term safety. Specifically, some studies suggest a possible link to cases of stomach cancer caused by Prilosec or Nexium use, prompting further investigation into the risks of extended PPI use.
How Do PPIs Work?
Proton pump inhibitors work by reducing the amount of acid produced in the stomach. The drugs block the enzyme that produces stomach acids in the stomach walls. By doing so, they help heal any damage caused to the stomach lining by the acids produced, thereby providing relief to users from heartburn and indigestion.
Though PPIs are mostly safe in the short run, there have been growing concerns about their potential risks in the long run, especially when taken without medical advice and supervision.
PPIs and Stomach Cancer
With recent studies associating PPIs with stomach cancer, people have become extremely cautious about using these drugs. When you take PPIs, the body recognizes the low level of acid and produces the hormone gastrin. Excessive gastrin has been linked to gastrointestinal tumors. However, stomach cancer caused by Prilosec or Nexium use has lower rates than stomach cancer caused by H. pylori.
How was the Study Done?
The study, which examines the relationship between Nexium and Prilosec, was conducted in 2017. The study was only done involving patients who were being treated for H. pylori infection, which can significantly increase the risk of stomach cancer. In the study, a few patients continued using PPIs for much longer after the eradication of H. pylori infection. It was found that those who continued to use the PPIs had a 2.4 times higher risk of stomach cancer.
Is There a Need for Worry?
These studies just show an association of increased risk of cancer caused by long-term PPI use and not an exact relation. Apart from that, various underlying factors such as diet, genetics, age, smoking, and other underlying medical conditions can also influence stomach cancer. If you have been taking Nexium, Prilosec, or other PPIs, there is no need to worry; simply ensure that you don’t exceed the prescribed timeframe.
What to Do if Nexium or Prilosec Affects You
If you or anyone you know has been affected due to the use of Nexium or Prilosec, you can always file a lawsuit to get compensation. It may help you cover your medical costs or compensate for any emotional distress it may have caused you.
Final Thoughts
The link between Nexium, Prilosec, and stomach cancer is something that needs to be looked at, but there is no need for alarm. When used appropriately, they are safe and effective. By ensuring that these drugs are not used long-term, you can prevent any issues caused by them.
